Unique Features

CDISC compliant database allowing the data to be shared directly with the FDA for analyses around safety and efficacy as part of a formal MOU (#225-13-0012) executed in 2013. HCV-TARGET developed standardized, centralized chart data abstraction methods along data...

Aims

Primary aims: Safety and efficacy in populations represented and underrepresented in phase III clinical trials African Americans / Hispanics, cirrhosis, null responders, age > 65, transplant Subgroup analyses to determine the cumulative influence of IL28B, fibrosis,...

Phase 2

Longitudinal, observational study Prospective and sequential Inclusion criteria: Adult patients (≥ 18 years) being treated with any anti-HCV regimen outside of a clinical trial Exclusion criteria: Inability to provide written informed consent Biorepository: baseline...

Phase 1

Longitudinal, observational study Inclusion criteria: All adult patients (older than age 18) being treated with antiviral regimens that contain telaprevir or boceprevir Ability to provide written informed consent for participation Exclusion criteria: Inability to...
HCV-TARGET Team

HCV-TARGET Team

Led jointly by the University of Florida and the University of North Carolina at Chapel Hill, HCV-TARGET is an international research consortium created to inform the ongoing transformation of hepatitis C treatment and research.   Steering Committee Michael Fried,...